I think that #'1 and 4 are on separate coils, so I dunno if that'd be the problem. Replace the wires, and see where you are. It wouldn't hurt to check the individual connections to each coil either. Also, I've seen where you can get enough water or oil contamination down in the spark plug valley to where the wires just spark out to the aluminum head, instead of the plugs. Make sure that the areas around where the spark plugs sit is completely clean and dry. Be sure NOT to knock any dirt/crap into the spark plug holes, though.